Online resources and papers
This list of bioinformatics tutorials, papers, and other online resources may be helpful to you in this class. We welcome additions to the list. If you find a website that was helpful to you, please let us know.
Contributed units to Current Protocols series
- Basic Protein Sequence Analysis, Current Protocols in Molecular Biology (invited unit). This pre-print is a resource for you to use in a variety of projects, giving explicit "how-to" instructions on using a number of resources and interpreting their results.
- Phylogenomic inference of protein molecul
ar function, Current Protocols in Bioinformatics (invited unit). This pre-print gives you a guided tutorial of how to perform phylogenomic inference, from gathering homologs and alignment to identifying functional subfamilies.
Core Bioinformatics Tutorials
Guides/tutorials written by members of our group for this class
Protein structure analysis
Help with Unix
More biology background
Molecular Biology for Computer Scientists A guide for those who need a little biology review.
Molecular clock discussion, and another discussion of molecular clocks.
Critical thinking
Statistics
HyperStat Online: Logic of Hypothesis Testing">. This resources has a number of pages you can navigate to with useful information.
Multivariate Unit Intro (online course) developed by Manchester Metropolitan University, UK. Hypertext guide to many interesting applications of statistical analysis to biological (and other) data.
StatSoft overview of cluster analysis .
Online Tutorial with relevant guidelines for interpreting statistical tests: Clinical Epidemiology for Effective Clinical Practice.
Chestx-ray.com's handy sensitivity/specificity calculator.
Type 1 and Type II errors, etc..
Nice tutorial/review of ROC curves, including a Java applet to motivate the tradoff between sensitivity and selectivity.
Web resources explaining mathematical underpinnings of bioinformatics methods